Laboratory of Cancer Genomics

Japanese

Introduction:

Our laboratory aims to find characteristic genome copy aberrations, epigenetic abnormalities as well as gene expression profiles in cancer by using microarray (DNA chip) -based whole genome analyses and to utilize them to identify cancer-related genes and develop tumor risk classification system. We currently focus our effort on brain tumor and lung cancer as well as pediatric cancers such as neuroblastoma and hepatoblastoma.

Key Words: Genome analysis, Microarray, DNA chip, Array CGH,
Gene expression profile, Mutation, Prognosis prediction,
Tumor classification, Risk classification, Personalized medicine

Members:

ChiefMiki Ohira

Senior ResearcherEriko Isogai

Visiting ResearcherMakoto Suzuki (Chiba University Hospital)
Mitsuru Yoshino (Chiba University Hospital)

Technical AssistantOsamu Ishikawa

Research projects:

Combined genomic and gene expression profiling of cancer and its clinical application

1. Integrated genomic and genetic analysis to develop cancer therapeutic strategy
2. Translational research of pediatric cancers (collaborative Res Project)
3. Cancer genome medicine: Genomic diagnosis and molecular-targeted therapy (collaborative Res Project)