Laboratory of Innovative Cancer Therapeutics

Japanese

Introduction:

Our laboratory aims to unveil molecular mechanisms of cancers, especially those of carcinogenesis and spontaneous regression of neuroblastoma. We also identify the important genes which could be therapeutic targets by using comprehensive genome analyses, comprehensive expression profiles and candidate genes approach including p53 family members.

Key Words: Carcinogenesis, Neuroblastoma, Spontaneous regression, Molecular targets, Drug discovery

Members:

Head（Director）Akira Nakagawara

Senior ResearcherYohko Nakamura

Postdoctoral Fellow Tomoki Yokochi
Sonia Kramer
Dan Wu
S.M. Rafigul Islam

Graduate StudentKoji Ando
Daisuke Takagi
Fan Yu

Graduate School of Medicine, Chiba University Steven Larsen
Yusuke Suenaga
Ryo Takano
Jesmin Akter
M.D.Ajijur Rahman
M.D.Kamrul Hasan
Shogo Kojima
Yoshiki Kaneko

Student Daisuke Matsumoto

Technical AssistantAkane Sata
Rumiko Murasugi
Kumiko Hata
Toshiko Yoshida

Research projects:

Unveiling molecular mechanisms of carcinogenesis, progression and spontaneous regression of cancers, especially of neuroblastoma; Establishing the system of the outcome prediction of cancer patients; and Development of novel therapeutic strategies of cancers.

1. Unveiling spontaneous regression of neuroblastoma and its application to the therapy
2. Molecular target therapy for cure of cancer
3. p53 family genes and carcinogenesis/metastasis（collaborative Res Project）
4. Practical translational research of pediatric cancers（collaborative Res Project）
5. -IBM social contribution program-
   Help Fight Childhood Cancer (HFCC) project [World Community Grid]