Research Institute

Laboratory of Anti-tumor Research

Japanese

Introduction:

Our aim is to understand the precise molecular mechanisms behind DNA damage response, especially the possible involvement of tumor suppressor p53 family members including p53, p73 and p63. In addition, we are interested in functional significance of candidate stem cell marker CD133 which might contribute to the genesis and progression of tumors.

Key Words: p53 family、DNA damage, Anti-cancer drug, Apoptosis

Members:

Photos

ChiefToshinori Ozaki

ResearcherOsamu Shimozato

Postdoctoral FellowRintaro Okoshi

Graduate School of Medicine, Chiba UniversitySerina Matsushita

StudentNatsumi Kubo
Kumiko Nakashima

Research projects:

Elucidation of the precise molecular mechanisms behind DNA damage response; Functional analysis of candidate stem cell marker CD133

  1. Molecular Mechanisms of DNA damage response and repair
  2. p53 family genes and carcinogenesis/metastasis (collaborative Res Project)
  3. Stem cells and carcinogenesis/metastasis (collaborative Res Project)

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