Chiba Cancer Center Research Institute
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Div Pathology

1  Members

  Head: 
        Masatoshi Tagawa
  Senior Investigator:
        Kiyoko Kawamura
        Shigenobu Mochizuki
        Nobuko Koshikawa
  Investigator:
        Osamu Shimozato
        Hisanori Takenobu
  Graduate Student: 
        Li Quanhai
        Ma Guangyu
        Wu Yaqiong
        Ayako Sato
  Assistant Staff: 
        Akiko Fukuda

2  Research Projects

        Under Construction 

3  Selected papers (2002-present)  --- Publication List

1. Chiyo, M., Shimozato, O., Yu, L., Kawamura, K., Iizasa, T., Fujisawa, T. and Tagawa, M.: Expression of IL-27 in murine carcinoma cells produces antitumor effects and induces protective immunity in inoculated host animals. Int. J. Cancer 115: 437-442, 2005. 

2. Yu, L., Hamada, K., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S. and Tagawa, M.: Midkine promoter-driven suicide gene expression and -mediated adenovirus replication produced cytotoxic effects to immortalized and tumour cells. Eur. J. Cancer 40: 1787-1794, 2004.

3. Wang, Y-Q., Ugai, S., Shimozato, O., Yu, L., Kawamura, K., Yamamoto, H., Yamaguchi, T., Saisho, H. and Tagawa, M.: Induction of systemic immunity by expression of interleukin-23 in murine colon carcinoma cells. Int. J. Cancer 105: 820-824, 2003.

4. Tada, Y., O-Wang, J., Takiguchi, Y., Tatsumi, K., Kuriyama, T., Okada, S., Tokuhisa, T., Sakiyama, S. and Tagawa, M.: A novel role for Fas ligand in facilitating antigen acquisition by dendritic cells. J. Immunol. 169: 2241-2245, 2002.

5. Miyauchi, M., Yoshida, Y., Tada, Y., Narita, M., Maeda, T., Bahar, R., Kadomatsu, K., Muramatsu, T., Matsubara, S., Nakagawara, A., Sakiyama, S. and Tagawa, M.: Expression of herpes simplex virus-thymidine kinase gene controlled by a promoter region of the midkine gene confers selective cytotoxicity to ganciclovir in human carcinoma cells. Int. J. Cancer 91: 723-727, 2001